Mayor Carlo DeMaria said in a statement Monday night he's "excited to see how Wynn's vision for this site may complement my vision" for the future.
A spokesman for Wynn Resorts declined to comment.
The Boston Globe, which reported Wynn's interest (http://bo.st/110q9y4) said a top Wynn executive has recently viewed the former Monsanto Chemical sight, and Wynn is expected to this week.
In May, Wynn suspended efforts to bring a $1 billion casino resort to Foxborough on land to be leased from New England Patriots owner Robert Kraft after the town turned aside efforts to negotiate a development proposal.
Suffolk Downs and Caesars Entertainment have applied for casino development rights at the East Boston race track.
