PHILADELPHIA (AP) -- Sherwood Brown scored 24 points and Bernard Thompson had 23 to lead Florida Gulf Coast to an incredible NCAA tournament debut, a 78-68 win over second-seeded Georgetown on Friday night in the second round of the South Regional.

The Eagles, in their second season of being eligible for Division I postseason, became just the seventh No. 15 seed to beat a No. 2.

FGCU (25-10) will play the winner of the game between seventh-seeded San Diego State and No. 10 Oklahoma in the third round on Sunday.

A night after America's oldest university, Harvard, pulled off a major upset over fourth-seeded New Mexico, one of its youngest -- FGCU's first student was admitted in 1997 -- got one that was even bigger.

The Eagles took control with a 21-2 run that gave them a 52-33 lead with 12:28 to play, though the Hoyas used a furious rally to get within 72-68 with 52 seconds left.

It was another disappointing NCAA exit for the Hoyas (25-7), who have lost to a double-digit seed in their last four appearances.

Markel Starks had 23 points for the Hoyas.