“Whether she runs or not will not affect my decision,” Biden said during an interview on ABC’s daytime talk show “The View.”
“Its as likely I run as I don’t run,” he added. “I just truly haven’t made up my mind.”
Biden has declined to close the door on a possible run, despite polls showing him a distant second to former Secretary of State Clinton for the Democratic nomination.
Clinton’s supporters have begun laying the groundwork for her to run, but she has sidestepped questions about her future, telling ABC in an interview in December that she would make a decision sometime next year.
The vice president said that he would run if he believed he was the best candidate to press forward President Obama's agenda, citing his work on foreign policy and to help bolster the middle class.
“I think my knowledge of foreign policy, my engagement with world leaders, my experience uniquely positions me to be, to follow through on the agenda that Barack and I have of bringing up world peace in a way that is real and substantive,” he said.
Biden also cited his concerns for the middle class, calling it the “single focus, what we should be looking at, how to grow it.”
But the vice president cautioned that Democrats should stay focused on the approaching 2014 midterms.
“The first objective here is to win the House and keep the Senate, because if we don’t do that, our agenda is not going to be worth very much in the last two years,” said Biden.
In an interview with CNN earlier this month, Biden said there was “no obvious reason” why he shouldn’t run for in 2016.
“There may be reasons I don’t run, but there’s no obvious reason for me why I think I should not run,” the vice president said.
“Tell you what, I’ll make you a deal, if you stick around, I will announce my decision with you,” Biden also promised host Barbara Walters.