"God bless you for being here today!" Cruz said Tuesday, after wading into the crowd and stepping up to the podium.
Activists cheered Cruz's arrival after spending several hours standing in the snow in front of the court during oral arguments inside.
"Thank you for being here in this beautiful weather from God," Cruz added as the crowd laughed.
Cruz reminded activists that the United States was founded by people who fled religious oppression and enshrined religious freedom in the Constitution.
"There is a reason why the first protection in the Bill of Rights was the right to religious freedom," he said.
Cruz pointed out that the Obama administration had given Obamacare exemptions to powerful special interests, but refused to exempt people of faith from the contraception mandate.
"And yet the position of this administration is that people of faith do not deserve an exemption, people of faith do not have a right to practice their faith," he said.
Cruz explained to pro-choice protestors at the Supreme Court that the case had nothing to do with their individual right to use birth control.
"No one is doubting that any person, if they choose to use contraceptives can do so. This is not about that," he said. "This is about the federal government, whether they can force people of faith to violate their own faith by paying for something that is contrary to the dictates and teachings of their faith."
Cruz pointed out that the administration was litigating against the Little Sisters of the Poor, who are facing fines for not complying with the individual mandate.
"Now, any individual can choose to exercise whatever they want, but the idea that we are trying to fine Catholic nuns millions of dollars to force them to violate their faith, that runs utterly contrary to centuries of tradition to the protection of our Constitution," he said.
Cruz boldly predicted that the high court would side with the owners of Hobby Lobby.
"I predict that the United States Supreme Court is going to strike down the contraception mandate because they are going to say, 'the federal government does not have the authority to force people to violate their faith particularly when they are granting exemptions to every other powerful interest.'" he said. "They can't single out people of faith and say, 'you will be treated worse than big business, worse than members of Congress.'"